Lock & Dam #10 is located right in Guttenberg, Iowa. The lock is undergoing maintenance from 2006 to 2008, so the visitor area is closed during that time period. The lock features a standard 600 foot long by 110 foot wide lock. The dam has four roller gates and 8 Tainter gates in the main structure, plus approximately 6,000 feet of earthen embankments that includes a 1,200 foot concrete spillway on the Wisconsin side of the river.

Guttenberg was once a major center for the button cutting industry, which was a major industry on the Mississippi River during the 1800s. Today, Guttenberg exists largely to support the tourism and recreation industry. Guttenberg is located in an region called the Driftless Area, which covers southwest Wisconsin, southeast Minnesota, and parts of Illinois and Iowa along the great river. The Driftless Area was not covered by the most recent ice age, which means that the rough terrain and bluffs were not leveled by the glaciers. The result is a landscape that looks more like West Virginia than Iowa, and certainly explodes the myth that Iowa is the home of the flatlanders.